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Biological Activity
Begacestat is a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.53 mL | 127.64 mL | 255.27 mL |
| 0.5 mM | 5.11 mL | 25.53 mL | 51.05 mL |
| 1 mM | 2.55 mL | 12.76 mL | 25.53 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.11 mL |
*The above data is based on the productmolecular weight 391.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11258 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 769169-27-9 |
| Formula | C9H8ClF6NO3S2 |
| M. Wt | 391.74 |
| Purity | >98% |
| Synonyms | GSI953, GSI 953 |
| SMILES | C1=C(SC(=C1)Cl)S(=O)(=O)NC(CO)C(C(F)(F)F)C(F)(F)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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