β-lactamase

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  1. BRL-42715

    Catalog No. A20726
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    β-lactamase inhibitor
    BRL-42715 is a potent inhibitor of a broad range of bacterial beta-lactamases (β-lactamase) . Learn More
  2. Vaborbactam

    Catalog No. A20638
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    β-lactamase inhibitor
    Vaborbactam is a cyclic boronic acid pharmacophore β-lactamase inhibitor. Learn More
  3. Taniborbactam

    Catalog No. A20232
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    β-lactamase inhibitor
    Taniborbactam is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections. Learn More
  4. Nacubactam

    Catalog No. A19471
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    non-β-lactam-β-lactamase inhibitor
    Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and class C β-lactamases. Learn More
  5. Zidebactam sodium salt

    Catalog No. A21896
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    β-lactamase inhibitor
    Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. Learn More
  6. Avibactam sodium

    Catalog No. A17306
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    non-β-lactam β-lactamase inhibitor
    Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively. Learn More
  7. VNRX-5133

    Catalog No. A18824
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    β-lactamase inhibitor
    VNRX-5133 is a cyclic boronate β-lactamase inhibitor. Learn More
  8. Zidebactam

    Catalog No. A18722
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    β-lactamase inhibitor
    Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. Learn More
  9. AAI101

    Catalog No. A18341
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    β-lactamase inhibitor
    AAI-101, also known as Enmetazobactam, is a beta lactamase inhibitor potentially for the treatment of multi-drug resistant gram-negative bacterial infections. Learn More
  10. Clavulanic acid

    Catalog No. A12384
    Clavulanic acid is a mechanism-based β-lactamase inhibitorcombined with penicillin group antibiotics to overcome certain types of antibiotic resistance. Learn More
  11. Sulbactam

    Catalog No. A11648
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    β-lactamase inhibitor
    Sulbactam is a beta-lactamase inhibitor with an average IC50 of 0.8 μM. Learn More
  12. Avibactam

    Catalog No. A11299
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    β-lactamase inhibitor
    Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor. Learn More

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