BG45

Catalog No.: A11361

HDAC inhibitor

BG45

BG45 Chemical Structure

CAS NO. 926259-99-6

BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively).

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$70.00
50 mg
$200.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively).
Targets
HDAC3 HDAC1 HDAC2 HDAC6
289 nM2 μM2.2 μM>20 μM
In vitro DMSO 40 mg/mL (186.72 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (9.33 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.68 mL 233.4 mL 466.81 mL
0.5 mM 9.34 mL 46.68 mL 93.36 mL
1 mM 4.67 mL 23.34 mL 46.68 mL
5 mM 0.93 mL 4.67 mL 9.34 mL

*The above data is based on the productmolecular weight 214.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11361
Actions Inhibitor
CAS No. 926259-99-6
Formula C11H10N4O
M. Wt 214.22
Solubility DMSO
Purity >98%
Synonyms BG 45, BG-45
SMILES NC1=CC=CC=C1/N=C(O)/C2=CN=CC=N2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy BG45 | BG45 Supplier | purchase | cost | manufacturer | order | distributor | buy 926259-99-6| 926259-99-6 Supplier | purchase 926259-99-6 | 926259-99-6 cost | 926259-99-6 manufacturer | order 926259-99-6 | 926259-99-6 distributor
Rewards