BG45

Catalog No.: A11361

HDAC inhibitor

BG45 Chemical Structure

CAS NO. 926259-99-6

BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively).

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$70.00
50 mg
$200.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively).
Targets
HDAC3 HDAC1 HDAC2 HDAC6
289 nM2 μM2.2 μM>20 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.68 mL 233.4 mL 466.81 mL
0.5 mM 9.34 mL 46.68 mL 93.36 mL
1 mM 4.67 mL 23.34 mL 46.68 mL
5 mM 0.93 mL 4.67 mL 9.34 mL

*The above data is based on the productmolecular weight 214.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11361
Actions Inhibitor
M. Wt 214.22
Formula C11H10N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 926259-99-6
Synonyms BG 45, BG-45
SMILES NC1=CC=CC=C1/N=C(O)/C2=CN=CC=N2

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