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Biological Activity
BINA is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22 mL | 109.99 mL | 219.97 mL |
| 0.5 mM | 4.4 mL | 22 mL | 43.99 mL |
| 1 mM | 2.2 mL | 11 mL | 22 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
*The above data is based on the productmolecular weight 454.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11126 |
|---|---|
| Actions | Modulator |
| CAS No. | 866823-73-6 |
| Formula | C30H30O4 |
| M. Wt | 454.6 |
| Purity | >98% |
| Synonyms | Biphenyl-indanone A |
| SMILES | CC1=C(C=C2CC(C(=O)C2=C1C)C3CCCC3)OCC4=CC=CC(=C4)C5=CC=C(C=C5)C(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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