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BMY 7378


5-HT1A agonist

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Catalog No. A11208

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BMY 7378 10mg A11208-10

Regular Price: $40.00

Special Price: $36.00

BMY 7378 50mg A11208-50

Regular Price: $85.00

Special Price: $76.50

BMY 7378 200mg A11208-200

Regular Price: $320.00

Special Price: $288.00

BMY 7378 10mM * 1mL in DMSO A11208-10mM-D

Regular Price: $77.00

Special Price: $69.30

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BMY 7378 is a 5-HT1A partial agonist and high affinity α1D adrenoceptor antagonist.

BMY 7378

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Chemical Information

Catalog Num A11208
Actions Agonist
M. Wt 458.42
Formula C22H31N3O3.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 21102-95-4
Synonyms BMY7378, BMY-7378

Biological Activity

BMY 7378 is a 5-HT1A partial agonist and high affinity α1D adrenoceptor antagonist.
Target Value
5-HT1ApIC50: 8.3
α1D-adrenoceptorpki: 8.2
DopamineD2receptorpIC50: 7.4
α2C-adrenoceptorpki: 6.54
5-HT1CpIC50: 6.4
5-HT1DpIC50: 5.9
H1receptorpIC50: 5.7
5-HT2pIC50: 5.5
H2receptorpIC50: 5.3
α2-adrenoceptor pIC50: 5.1
β1-adrenoceptor pIC50: 5.1
DopamineD1receptorpIC50: 5
NicotinicreceptorpIC50: 4.9
β2-adrenoceptor pIC50: <5.0
5-HT3pIC50: <5.0
H3receptorpIC50: <5.0
GABAAreceptorpIC50: <5.0
GABABreceptorpIC50: <5.0
MuscarinicM1receptorpIC50: <5.0
MuscarinicM2receptorpIC50: <5.0
MuscarinicM3receptorpIC50: <5.0
NMDAreceptorpIC50: <5.0
AT1receptorpIC50: <5.0
AT2receptorpIC50: <5.0
EndothelinReceptorpIC50: <5.0
AdenosineA1receptorpIC50: <5.0
AdenosineA2receptorpIC50: <5.0


Solubility (25°C) * In vitro DMSO 92 mg/mL (200.68 mM)
Water 92 mg/mL (200.68 mM)
Ethanol 20 mg/mL (43.62 mM)
In vivo Saline 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.81 mL 109.07 mL 218.14mL
0.5 mM 4.36 mL 21.81 mL 43.63 mL
1 mM 2.18 mL 10.91 mL 21.81 mL
5 mM 0.44 mL 2.18 mL 4.36 mL

*The above data is based on the productmolecular weight 458.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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