Brivanib alaninate (BMS-582664)

Catalog No.: A10162

VEGFR inhibitor

Brivanib alaninate (BMS-582664) Chemical Structure

CAS NO. 649735-63-7

Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$168.00
25 mg
$368.00
50 mg
$688.00
10mM * 1mL in DMSO
$138.00

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Biological Activity

Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.
Targets
VEGFR2 Flk1 FGFR1 VEGFR1
25 nM89 nM148 nM380 nM
In vitro (25°C) DMSO 88 mg/mL (199.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 88 mg/mL (199.33 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10162
Actions Inhibitor
M. Wt 441.5
Formula C22H24FN5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 649735-63-7
Synonyms BMS582664
SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[[email protected]@H](C)OC(=O)[[email protected]](C)N)C

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