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Brivanib alaninate (BMS-582664)

Catalog No.: A10162

VEGFR inhibitor

Brivanib alaninate (BMS-582664)

Brivanib alaninate (BMS-582664) Chemical Structure

CAS NO. 649735-63-7

Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $168.00

Special Price $134.40

25 mg

Regular Price: $368.00

Special Price $294.40

50 mg

Regular Price: $688.00

Special Price $550.40

10mM * 1mL in DMSO

Regular Price: $138.00

Special Price $110.40

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Biological Activity

Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.
25 nM89 nM148 nM380 nM
In vitro (25°C) DMSO 83 mg/mL (188 mM)
Water Insoluble
Ethanol 83 mg/mL (188 mM)
In vivo 0.5% methylcellulose+0.2% Tween 80 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10162
Actions Inhibitor
CAS No. 649735-63-7
Formula C22H24FN5O4
M. Wt 441.5
Purity >98%
Synonyms BMS582664
SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[[email protected]@H](C)OC(=O)[[email protected]](C)N)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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