Brivanib (BMS-540215)

Name: Brivanib (BMS-540215)
SKU: A10254
Price: 30 USD
Rating: 5 (2 reviews)

Catalog No.: A10254

VEGFR-2 inhibitor

Adooq's Brivanib (BMS-540215) has been cited by 2 publications

Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.

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Grouped product items
Size	Price	Stock
1mg	$30.00	In stock
5mg	$85.00	In stock
10mg	$140.00	In stock
25mg	$265.00	In stock
50mg	$390.00	In stock
100mg	$580.00	In stock
200mg	$850.00	In stock
*10mM 1mL in DMSO**	$90.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Brivanib (BMS-540215) has been cited by 2 publications

Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932

Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

Biological Activity

Discription

Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.

Targets

Target	Value

Product Information

Catalog Num	A10254
Formula	C19H19FN4O3
Molecular Weight	370.4
CAS Number	649735-46-6
SMILES	CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)O)C
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	71 mg/mL (191.69 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (8.09 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27 mL	134.99 mL	269.98 mL
0.5 mM	5.4 mL	27 mL	54 mL
1 mM	2.7 mL	13.5 mL	27 mL
5 mM	0.54 mL	2.7 mL	5.4 mL

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