Brivanib (BMS-540215)

Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.
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Brivanib 5mg
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Brivanib 10mg
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Brivanib 50mg
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Brivanib 200mg
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Brivanib (BMS-540215) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's Brivanib (BMS-540215) has been cited by 2 publications
  • Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Biological Activity
    Discription Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.
    Target Value
    Product Information
    Catalog Num A10254
    Formula C19H19FN4O3
    Molecular Weight 370.4
    CAS Number 649735-46-6
    SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)O)C

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro DMSO 71 mg/mL (191.69 mM)
    Water Insoluble
    Ethanol 3 mg/mL (8.09 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27 mL 134.99 mL 269.98 mL
    0.5 mM 5.4 mL 27 mL 54 mL
    1 mM 2.7 mL 13.5 mL 27 mL
    5 mM 0.54 mL 2.7 mL 5.4 mL
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    Calculate the dilution required to prepare a stock solution.
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