Total item
Cart Subtotal
$0.00 Biological Activity
Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.
Targets
| Target | Value |
|---|---|
| VEGFR2 | IC50: 25nM |
| Flk1 | IC50: 89nM |
| FGFR1 | IC50: 148nM |
| VEGFR1 | IC50: 380nM |
| EGFR | IC50: >1.9μM |
| LCK | IC50: >2.5μM |
| PDGFRβ | IC50: >6μM |
| PKCα | IC50: >25μM |
| JAK3 | IC50: >50μM |
| In vitro | DMSO | 74 mg/mL (199.79 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 3 mg/mL (8.09 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27 mL | 134.99 mL | 269.98 mL |
| 0.5 mM | 5.4 mL | 27 mL | 54 mL |
| 1 mM | 2.7 mL | 13.5 mL | 27 mL |
| 5 mM | 0.54 mL | 2.7 mL | 5.4 mL |
*The above data is based on the productmolecular weight 370.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10254 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 370.4 |
| Formula | C19H19FN4O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 649735-46-6 |
| Synonyms | BMS540215 |
| SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[[email protected]@H](C)O)C |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Regorafenib (BAY 73-4506)
Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib (BAY 73-4506) is an ora…
Raf265 derivative
Raf265 derivative is a derivative of Raf265 that is an oral, highly selective RAF and VEGFR kinase inhibitor with IC50 of of 5 to 10 μM.
SU 5416 (Semaxinib)
SU 5416 is an inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and …
Tivozanib (AV-951)
Tivozanib (AV-951) is an oral VEGF receptor tyrosine kinase inhibitor that is designed to inhibit all three VEGF receptors.
Ki8751
Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-f…
TG 100572
TG 100572 is VEGFR2 and Src kinase inhibitor.
Vatalanib (PTK787) 2HCl
Vatalanib (PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis that inhibits all known VEGF receptors,…
(-)-Catechin gallate
(-)-Catechin gallate is an antioxidant constituent of green tea. At uM concentrations, inhibits VEGF-induced tyrosine phosphorylation.
Keywords:buy Brivanib (BMS-540215) | Brivanib (BMS-540215) Supplier | purchase Brivanib (BMS-540215) | Brivanib (BMS-540215) cost | Brivanib (BMS-540215) manufacturer | order Brivanib (BMS-540215) | Brivanib (BMS-540215) distributor | buy 649735-46-6| 649735-46-6 Supplier | purchase 649735-46-6 | 649735-46-6 cost | 649735-46-6 manufacturer | order 649735-46-6 | 649735-46-6 distributor
Adooq Quality Guarantee
We promise all products perform as described.