BRL-15572

Catalog No.: A11178

5-HT1D receptor antagonist

BRL-15572

BRL-15572 Chemical Structure

CAS NO. 193611-72-2

BRL-15572 is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.

Availability: Out of stock

Package Price
5 mg
$50.00
10 mg
$70.00
50 mg
$260.00
100 mg
$420.00
10mM * 1mL in DMSO
$103.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BRL-15572 is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.

Targets
Target Value
5-HT1Dpki: 7.9
5-HT1Apki: 7.7
5-HT2Bpki: 7.4
5-HT2Apki: 6.6
5-HT7pki: 6.3
5-HT2Cpki: 6.2
5-HT1Bpki: 6.1
5-HT1Fpki: 6
5-HT6pki: 5.9
5-HT1Epki: 5.2
In vitro (25°C) DMSO 96 mg/mL (200.05 mM)
Water <1 mg/mL (<1 mM)
Ethanol 40 mg/mL (83.35 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.55 mL 112.76 mL 225.52 mL
0.5 mM 4.51 mL 22.55 mL 45.1 mL
1 mM 2.26 mL 11.28 mL 22.55 mL
5 mM 0.45 mL 2.26 mL 4.51 mL

*The above data is based on the productmolecular weight 443.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11178
Actions Antagonist
M. Wt 443.42
Formula C25H27ClN2O.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 193611-72-2
Synonyms BRL15572
SMILES C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl

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