Biological Activity
BSI-201 is a potent inhibitor of PARP-1 and has been shown to cross the blood-brain barrier.
Targets
PARP1 (Cell-free assay) | ||||
In vitro | DMSO | 58 mg/mL (198.6 mM) | |
Water | <1 mg/mL (<1 mM) | ||
Ethanol | 28 mg/mL (95.88 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.25 mL | 171.23 mL | 342.47 mL |
0.5 mM | 6.85 mL | 34.25 mL | 68.49 mL |
1 mM | 3.42 mL | 17.12 mL | 34.25 mL |
5 mM | 0.68 mL | 3.42 mL | 6.85 mL |
*The above data is based on the productmolecular weight 292.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10164 |
---|---|
Actions | Inhibitor |
M. Wt | 292.0 |
Formula | C7H5IN2O3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 160003-66-7 |
Synonyms | BSI201, NSC-746045, IND-71677, Iniparib |
SMILES | C1=CC(=C(C=C1C(=O)N)[N+](=O)[O-])I |
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