BTZ043 (BTZ038, BTZ044)

Catalog No.: A10165

DprE1 inhibitor

BTZ043 (BTZ038, BTZ044) Chemical Structure

CAS NO. 957217-65-1

BTZ043 (BTZ038, BTZ044) inhibits decaprenylphosphoryl-β-d-ribose 2?-epimerase, which is an enzyme which produces the cell wall of the pathogenic bacterium Mycobacterium tuberculosis.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $126.00

Special Price $100.80

50 mg

Regular Price: $441.00

Special Price $352.80

100 mg

Regular Price: $968.00

Special Price $774.40

10mM * 1mL in DMSO
$137.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BTZ043 (BTZ038, BTZ044) inhibits decaprenylphosphoryl-β-d-ribose 2?-epimerase, which is an enzyme which produces the cell wall of the pathogenic bacterium Mycobacterium tuberculosis.
Targets
DprE1
In vitro (25°C) DMSO 22 mg/mL (50.99 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.18 mL 115.9 mL 231.8 mL
0.5 mM 4.64 mL 23.18 mL 46.36 mL
1 mM 2.32 mL 11.59 mL 23.18 mL
5 mM 0.46 mL 2.32 mL 4.64 mL

*The above data is based on the productmolecular weight 431.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10165
Actions Inhibitor
M. Wt 431.4
Formula C17H16F3N3O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957217-65-1
Synonyms BTZ038, BTZ044, BTZ-043
SMILES CC1COC2(O1)CCN(CC2)C3=NC(=O)C4=CC(=CC(=C4S3)[N+](=O)[O-])C(F)(F)F

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