CA-074

Catalog No.: A13256

Cathepsin B inhibitor

CA-074

CA-074 Chemical Structure

CAS NO. 134448-10-5

CA-074 is a potent inhibitor of cathepsin B with a Ki of 2 to 5 nM.

Availability: In stock

Package Price Qty
1 mg
$50.00
5 mg
$140.00
10 mg
$220.00
25 mg
$380.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Tianming Qiu, .et al. Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway, Cell Death Dis, 2018, Oct; 9(10): 946 PMID: 30237538

Biological Activity

CA-074 is a potent inhibitor of cathepsin B with a Ki of 2 to 5 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.08 mL 130.4 mL 260.8 mL
0.5 mM 5.22 mL 26.08 mL 52.16 mL
1 mM 2.61 mL 13.04 mL 26.08 mL
5 mM 0.52 mL 2.61 mL 5.22 mL

*The above data is based on the productmolecular weight 383.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13256
Actions Inhibitor
CAS No. 134448-10-5
Formula C18H29N3O6
M. Wt 383.44
Purity >98%
Synonyms CA074, CA 074
SMILES CCCNC(=O)[[email protected]@H]1C(O1)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)N2CCC[[email protected]]2C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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