Catalog No.: A10002

Raf inhibitor


PLX-4720 Chemical Structure

CAS NO. 918505-84-7

PLX-4720 is a B-raf inhibitor with IC50 of 160 nM.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $70.00

Special Price $56.00

25 mg

Regular Price: $100.00

Special Price $80.00

50 mg

Regular Price: $150.00

Special Price $120.00

100 mg

Regular Price: $240.00

Special Price $192.00

10mM * 1mL in DMSO
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.


PLX-4720 is a B-raf inhibitor with IC50 of 160 nM.
Target Value
C-Raf-1(Y340D/Y341D)IC50: 6.7nM
B-Raf(V600E)IC50: 13nM
BRKIC50: 130nM
B-RafIC50: 160nM
FRKIC50: 1.3μM
CSKIC50: 1.5μM
SrcIC50: 1.7μM
FAKIC50: 1.7μM
FGFRIC50: 1.9μM
KDRIC50: 2.3μM
HGKIC50: 2.8μM
CSF-1RIC50: 3.3μM
AuroraAIC50: 3.4μM
In vitro (25°C) DMSO 83 mg/mL (200.56 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% CMC/0.5% Tween-80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.17 mL 120.83 mL 241.66 mL
0.5 mM 4.83 mL 24.17 mL 48.33 mL
1 mM 2.42 mL 12.08 mL 24.17 mL
5 mM 0.48 mL 2.42 mL 4.83 mL

*The above data is based on the productmolecular weight 413.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10002
Actions Inhibitor
M. Wt 413.8
Formula C17H14ClF2N3O3S
Solubility DMSO>83mg/mL Water <1mg/mL Ethanol <1mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 918505-84-7
Synonyms PLX4720

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