GDC-0879

Catalog No.: A10420

B-Raf inhibitor

GDC-0879

GDC-0879 Chemical Structure

CAS NO. 905281-76-7

GDC-0879 is a specific inhibitor of B-Raf kinase enzyme,targeting B-Raf (V600E) (IC50: 0.13 nM).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $160.00

Special Price $128.00

25 mg

Regular Price: $300.00

Special Price $240.00

50 mg

Regular Price: $520.00

Special Price $416.00

10mM * 1mL in DMSO
$119.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

GDC-0879 is a specific inhibitor of B-Raf kinase enzyme,targeting B-Raf (V600E) (IC50: 0.13 nM).
Targets
B-Raf (A375, Colo205 cells)
0.13 nM
In vitro (25°C) DMSO 67 mg/mL (200.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (14.95 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.9 mL 149.52 mL 299.04 mL
0.5 mM 5.98 mL 29.9 mL 59.81 mL
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10420
Actions Inhibitor
M. Wt 334.4
Formula C19H18N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 905281-76-7
Synonyms GDC0879
SMILES C1C/C(=N\O)/C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy GDC-0879 | GDC-0879 Supplier | purchase GDC-0879 | GDC-0879 cost | GDC-0879 manufacturer | order GDC-0879 | GDC-0879 distributor | buy 905281-76-7| 905281-76-7 Supplier | purchase 905281-76-7 | 905281-76-7 cost | 905281-76-7 manufacturer | order 905281-76-7 | 905281-76-7 distributor
Rewards