JNK-IN-8

Catalog No.: A12749

JNK Inhibitor

JNK-IN-8

JNK-IN-8 Chemical Structure

CAS NO. 1410880-22-6

JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$180.00
25 mg
$300.00
50 mg
$540.00
10mM * 1mL in DMSO
$123.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively
In vitro DMSO 100 mg/mL heating (197 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.7 mL 98.5 mL 197.01 mL
0.5 mM 3.94 mL 19.7 mL 39.4 mL
1 mM 1.97 mL 9.85 mL 19.7 mL
5 mM 0.39 mL 1.97 mL 3.94 mL

*The above data is based on the productmolecular weight 507.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12749
Actions Inhibitor
M. Wt 507.59
Formula C29H29N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1410880-22-6
Synonyms N/A
SMILES CC1=C(C=CC(=C1)NC(=O)C2=CC(=CC=C2)NC(=O)/C=C/CN(C)C)NC3=NC=CC(=N3)C4=CN=CC=C4

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