Search results for '2c i hcl'

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  1. Rapamycin (Sirolimus)

    Catalog No. A10782-2500
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    mTOR Inhibitors
  2. NSC 95397 100mg

    Catalog No. A11470-100
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    Phosphatase inhibitor
  3. Lapatinib Ditosylate 10g

    Catalog No. A10514-10000
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  4. WS 12 10000mg

    Catalog No. A17046-10000
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    TRPM8 Agonist
  5. Sulfamethoxazole sodium

    Catalog No. A17452
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    Sulfamethoxazole sodium is an antibiotic used for bacterial infections. Learn More
  6. EIDD-1931

    Catalog No. A16510
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    EIDD-1931 is a novel nucleoside analog and behaves as a potent anti-virus agent. Learn More
  7. PF-07321332

    Catalog No. A20539
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    PF-07321332 is an orally bioavailable 3C-like protease (3CLPRO) inhibitor. Learn More
  8. Deoxycorticosterone Acetate

    Catalog No. A16490
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    Deoxycorticosterone acetate (DOCA) is a corticosteroid. Learn More
  9. Liothyronine sodium

    Catalog No. A20353
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    Liothyronine sodium is a thyroid hormone (T3) analog. It promotes adipogenic differentiation of MSCs. Learn More
  10. Daurichromenic acid

    Catalog No. A15624
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    Daurichromenic acid is a terpenophenol with a potent anti-HIV activity. Learn More
  11. Ranitidine

    Catalog No. A17721
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    Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Learn More
  12. Remimazolam

    Catalog No. A22200
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    benzodiazepine derivative drug
    Remimazolam, also known as CNS-7056, is a benzodiazepine derivative drug, developed by PAION, in collaboration with Japanese licensee Ono Pharmaceutical as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures. Learn More
  13. Pemafibrate

    Catalog No. A22201
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    PPAR alpha agonist
    Pemafibrate, also known as (R)-K 13675, is a PPAR alpha agonist. Learn More
  14. Avacopan

    Catalog No. A22202
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    selective C5aR antagonist
    Avacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist. Learn More
  15. Perlapine

    Catalog No. A22204
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    hM3Dq DREADD agonist
    Perlapine is a potent and selective hM3Dq DREADD agonist (EC50 = 2.8 nM). This drug exhibits >10,000-fold selectivity for hM3Dq over hM3. Learn More
  16. Durlobactam sodium

    Catalog No. A13801
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    beta-lactamase inhibitor drug candidate
    Durlobactam, also known as ETX2514, is a beta-lactamase inhibitor drug candidate. Learn More
  17. Ozogamicin

    Catalog No. A12672
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    antibody-drug conjugate Linker
    Ozogamicin is an antibody-drug conjugate Linker. Learn More
  18. Etanercept

    Catalog No. A12009
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    TNF inhibitor
    Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Learn More
  19. Dehydroascorbic acid

    Catalog No. A12366
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    potent cerebroprotection
    Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. Learn More
  20. Emedastine

    Catalog No. A22158
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    histamine H1 receptor antagonist
    Emedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Learn More
  21. IACS-13909

    Catalog No. A22159
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    SHP2 allosteric inhibitor
    IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. Learn More
  22. CB-103

    Catalog No. A22160
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    protein-protein interaction (PPI) inhibitor
    CB-103 is a first-in-class, orally active protein-protein interaction (PPI) inhibitor of the NOTCH transcriptional activation complex. CB-103 has anti-tumor activity. Learn More
  23. CRBN modulator-1

    Catalog No. A22161
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    CRBN modulator
    CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM. Learn More
  24. ATR inhibitor 2

    Catalog No. A22162
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    ATR inhibitor
    ATR inhibitor 2 is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Learn More
  25. JSH-150

    Catalog No. A22164
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    CDK9 inhibitor
    JSH-150 is a highly selective and potent CDK9 inhibitor with an IC50 of 1 nM. Learn More
  26. Molnupiravir

    Catalog No. A22165
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    broad-spectrum antiviral activity
    Molnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19. Learn More
  27. Laninamivir octanoate

    Catalog No. A22166
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    neuraminidase (NA) inhibitor
    Laninamivir octanoate (CS-8958), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Learn More
  28. Conoidin A

    Catalog No. A22167
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    cell permeable inhibitor
    Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII). Learn More
  29. ML382

    Catalog No. A22168
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    MRGPRX1 positive allosteric modulator
    ML382 is a potent and selective MRGPRX1 (Mas-related G protein-coupled receptor X1, MrgX1) positive allosteric modulator, with an EC50 of 190 nM. Learn More
  30. GRP-60367

    Catalog No. A22169
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    rabies virus (RABV) entry inhibitor
    GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. Learn More
  31. Lycorine

    Catalog No. A22170
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    SCAP inhibitor
    Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Learn More
  32. Eurycomanone

    Catalog No. A22171
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    Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. Learn More
  33. Gentiopicroside

    Catalog No. A22172
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    antianti-inflammatoryand antioxidative effects
    Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 ?M and 22.8 ?M for CYP2A6; Gentiopicroside has antianti-inflammatoryand antioxidative effects. Learn More
  34. Eleutheroside B1

    Catalog No. A22173
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    anti-human influenza virus efficacy
    Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 ?g/ml. Antiviral and anti-inflammatory activities. Learn More
  35. Periplogenin

    Catalog No. A22174
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    anti-psoriatic agent
    Periplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation. Learn More
  36. Oxyberberin

    Catalog No. A22175
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    natural alkaloid
    Berlambine is a natural alkaloid isolated from many plants. Learn More
  37. Groenlandicine

    Catalog No. A22176
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    protoberberine alkaloid
    Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Learn More
  38. 6-Methoxydihydroavicine

    Catalog No. A22177
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    antiplatelet activities
    6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro. Learn More
  39. S-23

    Catalog No. A22178
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    selective androgen receptor modulator
    S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. Learn More
  40. AC-262536

    Catalog No. A22179
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    selective androgen receptor (SAR) molecule
    AC-262536 is a selective androgen receptor (SAR) molecule. It has partial agonist activity with respect to testosterone and suppresses luteinizing hormone. Learn More
  41. NSC23005 free acid

    Catalog No. A22180
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    p18INK inhibitor
    NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM). Learn More
  42. MQAE

    Catalog No. A22181
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    fluorescent indicator
    MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. Learn More
  43. ML346

    Catalog No. A22182
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    activator of Hsp70 expression and HSF-1 activity
    ML346 is an activator of Hsp70 expression and HSF-1 activity, with an EC50 of 4.6 μM for Hsp70. Learn More
  44. ALK2-IN-1

    Catalog No. A22183
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    inhibitor of Activin receptor-like kinase (ALK2) mutant R206H
    ALK2-IN-1 (BLU-782) is a potent and selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of <10 nM. Learn More
  45. OTSSP167 hydrochloride

    Catalog No. A22184
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    MELK inhibitor
    OTSSP167 (hydrochloride) is a highly potent MELK inhibitor with IC50 value of 0.41 nM. Learn More
  46. BIO-013077-01

    Catalog No. A22185
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    antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4
    BIO-013077-01, Novel potent antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4. Learn More
  47. Practolol

    Catalog No. A22186
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    β1-adrenergic receptor antagonist
    Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias. Learn More
  48. Thiambutosine

    Catalog No. A22187
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    candidate for treatment of lepromatous leprosy
    Thiambutosine was a candidate for treatment of lepromatous leprosy. Learn More
  49. SSD114 hydrochloride

    Catalog No. A22188
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    GABAB receptor positive allosteric modulator
    SSD114 hydrochloride is a novel GABAB receptor positive allosteric modulator. Learn More
  50. GR 125743

    Catalog No. A22189
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    5-HT1B/1D receptor antagonis
    GR 125743 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively. Learn More

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