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Gliclazide
Catalog No. A11863 Gliclazide is used as an antidiabetic. It is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Learn More -
Felodipine
Catalog No. A10383 Felodipine is a 1,4-dihydropyridine antagonist and calcium channel protein inhibitor. Learn More -
Verapamil
Catalog No. A12679 Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Learn More -
Ceapin-A7
Catalog No. A22001 Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Learn More -
DL-AP5
Catalog No. A20527 DL-AP5 is the racemic version of the selective N-methyl-D-aspartate (NMDA) receptor antagonist. Learn More -
Sulfamethoxazole sodium
Catalog No. A17452 Sulfamethoxazole sodium is an antibiotic used for bacterial infections. Learn More -
EIDD-1931
Catalog No. A16510 EIDD-1931 is a novel nucleoside analog and behaves as a potent anti-virus agent. Learn More -
PF-07321332
Catalog No. A20539 PF-07321332 is an orally bioavailable 3C-like protease (3CLPRO) inhibitor. Learn More -
Deoxycorticosterone Acetate
Catalog No. A16490 Deoxycorticosterone acetate (DOCA) is a corticosteroid. Learn More -
Liothyronine sodium
Catalog No. A20353 Liothyronine sodium is a thyroid hormone (T3) analog. It promotes adipogenic differentiation of MSCs. Learn More -
Daurichromenic acid
Catalog No. A15624 Daurichromenic acid is a terpenophenol with a potent anti-HIV activity. Learn More -
Ranitidine
Catalog No. A17721 Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Learn More -
Remimazolam
Catalog No. A22200 benzodiazepine derivative drugRemimazolam, also known as CNS-7056, is a benzodiazepine derivative drug, developed by PAION, in collaboration with Japanese licensee Ono Pharmaceutical as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures. Learn More -
Pemafibrate
Catalog No. A22201 PPAR alpha agonistPemafibrate, also known as (R)-K 13675, is a PPAR alpha agonist. Learn More -
Avacopan
Catalog No. A22202 selective C5aR antagonistAvacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist. Learn More -
Perlapine
Catalog No. A22204 hM3Dq DREADD agonistPerlapine is a potent and selective hM3Dq DREADD agonist (EC50 = 2.8 nM). This drug exhibits >10,000-fold selectivity for hM3Dq over hM3. Learn More -
Durlobactam sodium
Catalog No. A13801 beta-lactamase inhibitor drug candidateDurlobactam, also known as ETX2514, is a beta-lactamase inhibitor drug candidate. Learn More -
Ozogamicin
Catalog No. A12672 antibody-drug conjugate LinkerOzogamicin is an antibody-drug conjugate Linker. Learn More -
Etanercept
Catalog No. A12009 TNF inhibitorEtanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Learn More -
Dehydroascorbic acid
Catalog No. A12366 potent cerebroprotectionDehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. Learn More -
Emedastine
Catalog No. A22158 histamine H1 receptor antagonistEmedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Learn More -
IACS-13909
Catalog No. A22159 SHP2 allosteric inhibitorIACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. Learn More -
CB-103
Catalog No. A22160 protein-protein interaction (PPI) inhibitorCB-103 is a first-in-class, orally active protein-protein interaction (PPI) inhibitor of the NOTCH transcriptional activation complex. CB-103 has anti-tumor activity. Learn More -
CRBN modulator-1
Catalog No. A22161 CRBN modulatorCRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM. Learn More -
ATR inhibitor 2
Catalog No. A22162 ATR inhibitorATR inhibitor 2 is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Learn More -
JSH-150
Catalog No. A22164 CDK9 inhibitorJSH-150 is a highly selective and potent CDK9 inhibitor with an IC50 of 1 nM. Learn More -
Molnupiravir
Catalog No. A22165 broad-spectrum antiviral activityMolnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19. Learn More -
Laninamivir octanoate
Catalog No. A22166 neuraminidase (NA) inhibitorLaninamivir octanoate (CS-8958), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Learn More -
Conoidin A
Catalog No. A22167 cell permeable inhibitorConoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII). Learn More -
ML382
Catalog No. A22168 MRGPRX1 positive allosteric modulatorML382 is a potent and selective MRGPRX1 (Mas-related G protein-coupled receptor X1, MrgX1) positive allosteric modulator, with an EC50 of 190 nM. Learn More -
GRP-60367
Catalog No. A22169 rabies virus (RABV) entry inhibitorGRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. Learn More -
Lycorine
Catalog No. A22170 SCAP inhibitorLycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Learn More -
Eurycomanone
Catalog No. A22171 Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. Learn More -
Gentiopicroside
Catalog No. A22172 antianti-inflammatoryand antioxidative effectsGentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 ?M and 22.8 ?M for CYP2A6; Gentiopicroside has antianti-inflammatoryand antioxidative effects. Learn More -
Eleutheroside B1
Catalog No. A22173 anti-human influenza virus efficacyEleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 ?g/ml. Antiviral and anti-inflammatory activities. Learn More -
Periplogenin
Catalog No. A22174 anti-psoriatic agentPeriplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation. Learn More -
Oxyberberin
Catalog No. A22175 natural alkaloidBerlambine is a natural alkaloid isolated from many plants. Learn More -
Groenlandicine
Catalog No. A22176 protoberberine alkaloidGroenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Learn More -
6-Methoxydihydroavicine
Catalog No. A22177 antiplatelet activities6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro. Learn More -
S-23
Catalog No. A22178 selective androgen receptor modulatorS-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. Learn More -
AC-262536
Catalog No. A22179 selective androgen receptor (SAR) moleculeAC-262536 is a selective androgen receptor (SAR) molecule. It has partial agonist activity with respect to testosterone and suppresses luteinizing hormone. Learn More -
NSC23005 free acid
Catalog No. A22180 p18INK inhibitorNSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM). Learn More -
MQAE
Catalog No. A22181 fluorescent indicatorMQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. Learn More -
ML346
Catalog No. A22182 activator of Hsp70 expression and HSF-1 activityML346 is an activator of Hsp70 expression and HSF-1 activity, with an EC50 of 4.6 μM for Hsp70. Learn More -
ALK2-IN-1
Catalog No. A22183 inhibitor of Activin receptor-like kinase (ALK2) mutant R206HALK2-IN-1 (BLU-782) is a potent and selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of <10 nM. Learn More
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