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BHMT2 Human
Catalog No. AP4965 Betaine-Homocysteine Methyltransferase 2 Human Recombinant Learn More -
BHMT Antibody
Catalog No. AP2680 Betaine Homocysteine S-Methyltransferase, Mouse Anti Human Learn More -
Alectinib Hydrochloride
Catalog No. A18000 ALK inhibitorAlectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Learn More -
GAP-134 Hydrochloride
Catalog No. A15092 Gap-junction modifierGAP-134 Hydrochloride, a small modified dipeptide, has been identified as a potent and selective second generation gap junction modifier with oral bioavailability. Learn More -
Defactinib hydrochloride
Catalog No. A22003 FAK inhibitorDefactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. Learn More -
Nevanimibe hydrochloride
Catalog No. A21767 ACAT1 inhibitorNevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Learn More -
Amsacrine hydrochloride
Catalog No. A17707 topoisomerase II inhibitorAmsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Learn More -
TGR-1202 hydrochloride (Umbralisib HCl)
Catalog No. A16278 PI3Kδ inhibitorTGR-1202 hydrochloride is an orally available, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 and 24.3 nM respectively. Learn More -
LMPTP INHIBITOR 1 dihydrochloride
Catalog No. A22227 LMPTP inhibitorLMPTP INHIBITOR 1 (dihydrochloride) is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A. Learn More -
LYN-1604 dihydrochloride
Catalog No. A22230 ULK1 activatorLYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC). Learn More -
HA-100 dihydrochloride
Catalog No. A22289 PKs inhibitorHA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 ?M, respectively). Learn More -
Iso-H7 dihydrochloride
Catalog No. A22368 inhibitor of phosphokinase CIso-H7 dihydrochloride is an inhibitor of phosphokinase C. Learn More -
Quisinostat dihydrochloride
Catalog No. A22453 pan-HDAC inhibitorQuisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan-HDAC inhibitor with IC50s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity. Learn More -
DAPI dihydrochloride
Catalog No. A22602 fluorescent probeDAPI Dihydrochloride is a cell-permeable fluorescent probe used to stain DNA and chromosomes, with a preference for adenine and thymine rich DNA. Learn More -
IT1t dihydrochloride
Catalog No. A22027 CXCR4 antagonistIT1t dihydrochloride is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. Learn More -
PAβN dihydrochloride
Catalog No. A22016 efflux pump inhibitorPAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor. Learn More -
IT1t
Catalog No. A20408 CXCR4 antagonistIT1t is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. Learn More -
SB-772077B dihydrochloride
Catalog No. A20090 ROCK inhibitorSB-772077B dihydrochloride is an aminofurazan-based Rho kinase (ROCK) inhibitor with IC50s of 5.6 nM and 6 nM toward ROCK1 and ROCK2, respevtively. Learn More -
XE 991 dihydrochloride
Catalog No. A20032 Kv7 (KCNQ) channels blockerXE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 ?M, 0.71 ?M, 0.6 μM, and 0.98 ?M, respectively. Learn More -
AZ10606120 dihydrochloride
Catalog No. A19853 P2X7R antagonistAZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10?nM. Learn More -
Dianicline dihydrochloride
Catalog No. A19775 α4β2 nicotinic acetylcholine receptor partial agonistDianicline dihydrochloride is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine for smoking cessation. Learn More -
ABT-702 dihydrochloride
Catalog No. A19624 AK inhibitorABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor (IC50=1.7 nM). Learn More -
Aminooxyacetic acid hemihydrochloride
Catalog No. A19408 MAS inhibitorAminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T. Learn More -
Hydroquinine
Catalog No. A17533 Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride. Learn More -
N-Desethyl amodiaquine dihydrochloride
Catalog No. A21695 N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. Learn More -
d-Atabrine dihydrochloride
Catalog No. A21654 d-Atabrine dihydrochloride is an active enantiomer of quinacrine which displays antiprion activity. Learn More -
Banoxantrone D12 dihydrochloride
Catalog No. A21438 Banoxantrone D12 dihydrochloride (AQ4N D12 dihydrochloride) is the deuterium labeled banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. Learn More -
Banoxantrone dihydrochloride
Catalog No. A21432 Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. Learn More -
Veliparib dihydrochloride
Catalog No. A21356 PARP inhibitorVeliparib dihydrochloride is a potent PARP inhibitor, inhibiting PARP1 and PARP2 with Kis of 5.2 and 2.9 nM, respectively. Learn More -
Ro 10-5824 dihydrochloride
Catalog No. A21986 dopamine D4 receptor partial agonistRo 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with Ki of 5.2 nM. Learn More -
LDN193189 Tetrahydrochloride
Catalog No. A21881 BMP type I receptor inhibitorLDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50??500 nM). Learn More -
MW-150 dihydrochloride dihydrate
Catalog No. A21860 p38α MAPK inhibitorMW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. Learn More -
Liarozole dihydrochloride
Catalog No. A21853 CYP450 dependent inhibitorLiarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase). Learn More -
B-Raf inhibitor 1 dihydrochloride
Catalog No. A21834 Raf kinase inhibitorB-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively. Learn More -
GSK-LSD1 dihydrochloride
Catalog No. A21815 LSD1 inhibitorGSK-LSD1 dihydrochloride is a potent, selective and irreversible lysine specific demethylase 1 (LSD1) inhibitor with an IC50 of 16 nM. Learn More -
DDR1-IN-1 dihydrochloride
Catalog No. A21813 DDR1 receptor tyrosine kinase inhibitorDDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM). Learn More -
Lexibulin dihydrochloride
Catalog No. A21774 tubulin polymerisation inhibitorLexibulin 2Hcl (CYT-997 2Hcl) is a potent tubulin polymerisation inhibitor with IC50 of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Learn More -
K-604 dihydrochloride
Catalog No. A21773 ACAT-1 inhibitorK-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45??0.06 μM. Learn More -
Philanthotoxin 74 dihydrochloride
Catalog No. A21739 AMPAR antagonistPhilanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. Learn More -
Ipatasertib dihydrochloride
Catalog No. A21734 pan-Akt inhibitorIpatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA. Learn More -
GSK3368715 dihydrochloride
Catalog No. A21733 PRMT inhibitorGSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). Learn More -
MCOPPB triHydrochloride
Catalog No. A21722 nociceptin receptor agonistMCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors. Learn More -
N8-Acetylspermidine dihydrochloride
Catalog No. A21720 N8-Acetylspermidine dihydrochloride is a polyamine. Learn More -
Lys01 trihydrochloride
Catalog No. A21702 lysosomal autophagy inhibitorLys01 trihydrochloride (Lys05) is a novel lysosomal autophagy inhibitor with IC50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay. Learn More -
TLR7/8 agonist 1 dihydrochloride
Catalog No. A21700 TLR7/8 agonistTLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. Learn More -
diABZI STING agonist-1 trihydrochloride
Catalog No. A21694 STING receptor agonistdiABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs. Learn More -
LCL521 dihydrochloride
Catalog No. A21656 ACDase inhibitorLCL521 dihydrochloride (1,3DMG-B13 dihydrochloride) is an acid ceramidase (ACDase) inhibitor. Learn More -
MRT68921 dihydrochloride
Catalog No. A21650 ULK1/ULK2 inhibitorMRT68921 dihydrochloride is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. Learn More
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