Search results for 'jwh 018'

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  1. NS-018 maleate

    Catalog No. A16226
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    JAK2 inhibitor
    NS-018 maleate is an ATP-competitive small-molecule inhibitor of JAK2 with IC50 of 470nM in Ba/F3-JAK2V617F cells . have30-50-fold greater selectivity for JAK2 over other JAK-family kinases, such as JAK1, JAK3 and tyrosine kinase 2. Learn More
  2. NS-018 hydrochloride

    Catalog No. A16225
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    JAK2 inhibitor
    NS-018 hydrochloride is a novel highly selective JAK2 inhibitor. Learn More
  3. NS-018

    Catalog No. A16224
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    JAK2 inhibitor
    NS-018 is an orally bioavailable, small molecule inhibitor of Janus-associated kinase 2 (JAK2) and Src-family kinases, with potential antineoplastic activity. Learn More
  4. PB-22

    Catalog No. A14110
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    PB-22 is an analog of JWH 018 which differs by having 8-hydroxyquinoline replacing the naphthalene group of JWH 018. Learn More
  5. LY 345899

    Catalog No. A19440
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    MTHFD1/MTHFD2 inhibitor
    LY 345899 is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 0.018 μM. Learn More
  6. Kv3 modulator 4

    Catalog No. A18951
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    Kv3.1/Kv3.2 modulator
    Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator extracted from patent WO2018020263A1, Cyclobutyl structure. Learn More
  7. Kv3 modulator 2

    Catalog No. A18965
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    Kv3 channels modulator
    Kv3 modulator 2 (formula (I)) is a potent Kv3 channels modulator extracted from patent WO2018109484A1, compound formula (I) , has analgesic activity and is used in the prophylaxis or treatment of related disorders. Learn More
  8. RET-IN-1

    Catalog No. A19015
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    RET inhibitor
    RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively . Learn More
  9. Fluopyram

    Catalog No. A19018
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    SDH inhibitor
    Fluopyram is a succinate dehydrogenase inhibitor fungicide, inhibits the growth of F. virguliforme isolates with mean EC50 of 3.35 ?g/mL. Learn More
  10. RIPK1-IN-3

    Catalog No. A19023
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    RIPK1 inhibitor
    RIPK1-IN-3 (Example 38), a RIPK1 inhibitor, extracted from patent WO2018148626A1, possesses anti-inflammatory proprieties. Learn More
  11. JAK1-IN-7

    Catalog No. A19029
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    JAK1 inhibitor
    JAK1-IN-7 is a Janus-associated kinase 1 (JAK1) inhibitor extracted from patent WO2018134213A1, Example 63, has an anti-inflammatory effect. Learn More
  12. KRAS G12C inhibitor 13

    Catalog No. A19041
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    KRAS G12C inhibitor
    KRAS G12C inhibitor 13 is a KRAS G12C inhibitor extracted from patent WO2018143315A1, compound 30. Learn More
  13. HIV-1 inhibitor-3

    Catalog No. A19110
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    HIV infection inhibitor
    HIV-1 inhibitor-3 is a HIV infection inhibitor extracted from patent US2018360927. Learn More
  14. AMG2850

    Catalog No. A19445
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    TRPM8 antagonist
    AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist. Learn More
  15. JNJ-632

    Catalog No. A20182
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    HBV capsid assembly modulator
    JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM). Learn More
  16. TP0463518

    Catalog No. A20183
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    PHD inhibitor
    TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. Learn More
  17. TPN171

    Catalog No. A18464
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    PDE5 inhibitor
    TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6. Learn More
  18. FGTI-2734

    Catalog No. A18578
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    FT/GGT dual inhibitor
    FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT, respectively. Learn More
  19. AKOS B018304

    Catalog No. A18719
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    AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position. Learn More
  20. GW284543

    Catalog No. A18808
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    MEK5 inhibitor
    GW284543, also known as UNC10225170;, is a potent and selective MEK5 inhibitor with the potential for cancer treatment. Learn More
  21. DO-264

    Catalog No. A18881
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    ABHD12 inhibitor
    DO-264 is a selective and in vivo-active inhibitor of Abhydrolase Domain Containing 12 (ABHD12), with an IC50 of 11 nM. Learn More
  22. Bendazac

    Catalog No. A17607
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    anticataract drug
    Bendazac, also known as Bendazolic acid and AF-983, is an anticataract drug. It has been reported that Bendazac acts by preventing protein denaturation. Learn More
  23. Levocetirizine Dihydrochloride

    Catalog No. A17440
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    Histamine H1 receptor antagonist
    Levocetirizine dihydrochloride is a L-isomer of cetirizine and histamine H1 receptor antagonist. It incrases levels of CD4+ CD25+ T cells and decreases levels of eosinophils, decreasing allergy symptoms. Learn More
  24. TLR7-agonist-1

    Catalog No. A17018
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    TLR7 agonist
    TLR7-agonist-1 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM. Learn More
  25. SR-17018

    Catalog No. A16902
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    MOR agonist
    SR17018 is an mu-opioid-receptor (MOR) agonist with an EC50 of 97 nM. Learn More
  26. Ruxolitinib Phosphate

    Catalog No. A11552
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    JAK inhibitor
    Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Learn More
  27. CagA Pylori

    Catalog No. AP6018
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    Helicobacter Pylori Cytotoxin-Associated Gene A Recombinant Learn More
  28. LIF Human, HEK

    Catalog No. AP5504
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    Leukemia Inhibitory Factor Human Recombinant, HEK Learn More
  29. LIF Human

    Catalog No. AP5500
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    Leukemia Inhibitory Factor Human Recombinant Learn More
  30. LIF Human, Yeast

    Catalog No. AP5499
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    LIF Human Recombinant, Yeast Learn More
  31. LIF Human, Sf9

    Catalog No. AP5498
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    Leukemia Inhibitory Factor Human Recombinant, Sf9 Learn More
  32. LIF Human, GST

    Catalog No. AP5497
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    Leukemia Inhibitory Factor, GST tag Human Recombinant Learn More
  33. UBE2L6 Human

    Catalog No. AP5018
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    Ubiquitin Conjugating Enzyme E2L 6 Human Recombinant Learn More
  34. LCN2 Human

    Catalog No. AP4193
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    Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 Human Recombinant Learn More
  35. LCN2 Human, His

    Catalog No. AP4192
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    Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 Human Recombinant, His Tag Learn More
  36. LCN2 Human, Pichia

    Catalog No. AP4191
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    Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 Human Recombinant, Pichia Learn More
  37. TDP2 Human

    Catalog No. AP4018
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    Tyrosyl-DNA Phosphodiesterase 2 Human Recombinant Learn More
  38. LGALS9 Human

    Catalog No. AP3474
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    Galectin-9 Human Recombinant Learn More
  39. PLP antibody

    Catalog No. AP3018
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    Proteolipid Protein of Myelin, Mouse antibody Learn More
  40. NT 3 Mouse

    Catalog No. AP2493
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    Neurotrophin-3 Mouse Recombinant Learn More
  41. SCGN Human

    Catalog No. AP2018
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    Secretagogin Human Recombinant Learn More
  42. SERPINB2 Human

    Catalog No. AP1018
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    Serpin Peptidase Inhibitor, Clade B Member 2 Human Recombinant Learn More
  43. IgG Mouse

    Catalog No. AP0282
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    Immunoglobulin Heavy Chain Constant Region Gamma 2a Mouse Recombinant Learn More
  44. IgG Mouse, His

    Catalog No. AP0281
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    Immunoglobulin Heavy Chain Constant Region Gamma 2a Mouse Recombinant, His Tag Learn More
  45. C20ORF20 Human

    Catalog No. AP0189
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    Chromosome 20 Open Reading Frame 20 Human Recombinant Learn More
  46. MLF1 Human

    Catalog No. AP0188
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    Myeloid Leukemia Factor 1 Human Recombinant Learn More
  47. PEF1 Human

    Catalog No. AP0187
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    Penta-EF-Hand Domain Containing 1 Human Recombinant Learn More
  48. EIF1AY Human

    Catalog No. AP0186
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    Eukaryotic Translation Initiation Factor 1A Y-linked Recombinant Human Learn More
  49. RAB1A Human

    Catalog No. AP0185
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    RAB1A, Member RAS Oncogene Family Recombinant Human Learn More
  50. SUGT1 Human

    Catalog No. AP0184
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    SGT1 Recombinant Human Learn More

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