Search results for 'ur 144'

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  1. SC-144

    Catalog No. A13660
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    gp130 inhibitor
    SC-144 is an orally active small-molecule gp130 inhibitor. Learn More
  2. EC 144

    Catalog No. A16056
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    HSP90 inhibitor
    EC 144 is a potent inhibitor of the heat shock protein 90 and was found to be effective in tumor growth suppression. Learn More
  3. Prodigiosin HCl

    Catalog No. A20938
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    Prodigiosin (Prodigiosine) HCl is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Learn More
  4. Formoterol Impurity G HCl

    Catalog No. A20735
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  5. Formoterol fumarate EP Impurity B

    Catalog No. A21015
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  6. Formoterol Dimer

    Catalog No. A21014
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  7. TAK-901

    Catalog No. A11067-150
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    Aurora Kinase A/B inhibitor
  8. Daurichromenic acid

    Catalog No. A15624
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    Daurichromenic acid is a terpenophenol with a potent anti-HIV activity. Learn More
  9. Remimazolam

    Catalog No. A22200
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    benzodiazepine derivative drug
    Remimazolam, also known as CNS-7056, is a benzodiazepine derivative drug, developed by PAION, in collaboration with Japanese licensee Ono Pharmaceutical as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures. Learn More
  10. Avacopan

    Catalog No. A22202
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    selective C5aR antagonist
    Avacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist. Learn More
  11. Durlobactam sodium

    Catalog No. A13801
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    beta-lactamase inhibitor drug candidate
    Durlobactam, also known as ETX2514, is a beta-lactamase inhibitor drug candidate. Learn More
  12. Laninamivir octanoate

    Catalog No. A22166
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    neuraminidase (NA) inhibitor
    Laninamivir octanoate (CS-8958), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Learn More
  13. Lycorine

    Catalog No. A22170
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    SCAP inhibitor
    Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Learn More
  14. Eurycomanone

    Catalog No. A22171
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    Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. Learn More
  15. Gentiopicroside

    Catalog No. A22172
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    antianti-inflammatoryand antioxidative effects
    Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 ?M and 22.8 ?M for CYP2A6; Gentiopicroside has antianti-inflammatoryand antioxidative effects. Learn More
  16. Periplogenin

    Catalog No. A22174
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    anti-psoriatic agent
    Periplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation. Learn More
  17. Oxyberberin

    Catalog No. A22175
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    natural alkaloid
    Berlambine is a natural alkaloid isolated from many plants. Learn More
  18. MQAE

    Catalog No. A22181
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    fluorescent indicator
    MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. Learn More
  19. SNG-1153

    Catalog No. A22222
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    modulator of estrogen receptor ER-alpha36
    SNG-1153 is a modulator of estrogen receptor ER-alpha36. Learn More
  20. KN-93 phosphate

    Catalog No. A22229
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    membrane-permeant synthetic inhibitor
    KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. Learn More
  21. TAE-1

    Catalog No. A22246
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    inhibitor of amyloid-β fibril formation and aggregation
    TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. TAE-1 inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively. Learn More
  22. Imidacloprid-urea

    Catalog No. A22253
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    marine xenobiotic metabolite
    Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid. Learn More
  23. Triphala

    Catalog No. A16067
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    Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities
    Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica. Triphala inhibits NF-κB activation. Triphala exerts antifungal action. Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities. Learn More
  24. Lignine

    Catalog No. A20324
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    Lignine (Lignin) is a complex organic polymer, which plays an important role in plant cell wall structure. Learn More
  25. Hypotaurine

    Catalog No. A20590
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    Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. Learn More
  26. Hyaluronidase

    Catalog No. A18232
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    local anesthetic additive
    Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive. Learn More
  27. Neuraminidase-IN-1

    Catalog No. A22065
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    neuraminidase inhibitor
    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus. Learn More
  28. CWP232228

    Catalog No. A22070
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    Wnt/β-catenin signaling inhibitor
    CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus. Learn More
  29. CRANAD-2

    Catalog No. A22076
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    near-infrared (NIR) probe
    CRANAD-2 is a curcumin-derivatized near-infrared (NIR) probe that meets all the requirements for a NIR contrast agent for the detection of Abeta plaques both in vitro and in vivo. Learn More
  30. 4BP-TQS

    Catalog No. A22084
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    neuronal nicotinic acetylcholine receptors agonist
    4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs). Learn More
  31. B355252

    Catalog No. A22086
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    neuroprotective agent
    B355252 is a neuroprotective agent potentiating nerve growth factor (NGF)-induced neurite outgrowth. Learn More
  32. YM26734

    Catalog No. A22091
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    rabbit platelet sPLA2 inhibitor
    YM-26734 is a rabbit platelet sPLA2 inhibitor that has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema. Learn More
  33. BPU-11

    Catalog No. A22101
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    HCN4 CLP ligand
    BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and completely abolishing the cAMP-induced shift in V1/2. Learn More
  34. Creatine riboside

    Catalog No. A22112
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    urinary metabolite
    Creatine riboside is a urinary metabolite and is a diagnostic and prognostic biomarker of lung cancer. Learn More
  35. MSBN

    Catalog No. A22114
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    fluorogenic probe
    MSBN is a highly selective fluorogenic probe for thiols, selectively imaging thiols in live cells and specifically label protein thiols with a turn-on signal to determine diverse reversible protein thiol modifications. Learn More
  36. Cytosporone B

    Catalog No. A22115
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    nuclear orphan receptor Nur77/NR4A1 agonist
    Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM. Learn More
  37. RGW 611

    Catalog No. A22135
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    anti-infective agent
    RGW 611, a morpholine derivative, is an impurity of Nimorazole, which is an anti-infective agent against anaerobic bacteria and protozoa. Learn More
  38. Pyrimorph

    Catalog No. A22144
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    Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Learn More
  39. Simetride

    Catalog No. A22153
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    non-narcotic analgesic
    Simetride, a non-narcotic analgesic, is an ingredient of Kyorin AP2 which is used to treat low back pain, symptomatic neuralgia, headache, menstrual pain and etc. Learn More
  40. Adenosine amine congener

    Catalog No. A22193
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    A1 adenosine receptor agonist
    Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and Cisplatin-induced cochlear injury. Learn More
  41. Remimazolam besylate

    Catalog No. A22198
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    ultra short-acting benzodiazepine
    Remimazolam besylate is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Learn More
  42. Zebularine

    Catalog No. A12721
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    DNA methyltransferase inhibitor
    Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor. Learn More
  43. Demethyleneberberine

    Catalog No. A22273
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    mitochondria-targeted antioxidant
    Demethyleneberberine is a natural mitochondria-targeted antioxidant. Learn More
  44. Ellagic acid (hydrate)

    Catalog No. A22282
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    ATP-competitive CK2 inhibitor
    Ellagic acid hydrate is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM. Learn More
  45. Amarogentin

    Catalog No. A22286
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    bitter taste receptor TAS2R1 agonist
    Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. Learn More
  46. Urolithin B

    Catalog No. A22287
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    regulator of skeletal muscle mass
    Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B is also a regulator of skeletal muscle mass. Learn More
  47. Tomatine

    Catalog No. A22293
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    precipitating agent
    Tomatine is an glycoalkaloid that occurs in the extract of leaves of wild tomato plants. It has been found to inhibit the growth of various fungi and bacteria. It is used as a precipitating agent for steroids. Learn More
  48. Acetosyringone

    Catalog No. A22294
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    anti-inflammatory agent
    Acetosyringone is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions. Learn More
  49. Ribociclib hydrochloride

    Catalog No. A22303
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    CDK4/6 inhibitor
    Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, Learn More
  50. BpV(HOpic)

    Catalog No. A22308
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    PTEN inhibitor
    BpV(HOpic) is a potent and selective inhibitor of PTEN with an IC50 of 14 nM. Nanocarrier-BpV(HOpic) has neuroprotective activity. Learn More

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