CFTR-Inhibitor-II

CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 uM).
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Product Name Price Stock Qty
CFTR-Inhibitor-II 5mg
Special Price $64.00 Regular Price $80.00
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CFTR-Inhibitor-II 10mg
Special Price $100.00 Regular Price $125.00
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CFTR-Inhibitor-II 25mg
Special Price $200.00 Regular Price $250.00
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Adooq Products cited in reputable paper
Adooq's CFTR-Inhibitor-II has been cited by 1 publications
  • Dao-Lai Zhang, .et al. , eLife, 2018, 7: e33432 PMID: 29393851
  • Biological Activity
    Discription CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 uM).
    Targets
    Target Value
    Product Information
    Catalog Num A13723
    Formula C19H15Br2N3O3
    Molecular Weight 493.2
    CAS Number 328541-79-3
    SMILES C1=CC=C2C=C(C=CC2=C1)NCC(=O)NN/C=C/3\C=C(C(=C(C3=O)Br)O)Br
    Synonyms GlyH-101, Cystic Fibrosis Transmembrane Conductance, Regulator Inhibitor II
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 91 mg/mL (184.53 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.28 mL 101.38 mL 202.76 mL
    0.5 mM 4.06 mL 20.28 mL 40.55 mL
    1 mM 2.03 mL 10.14 mL 20.28 mL
    5 mM 0.41 mL 2.03 mL 4.06 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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