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CGS 21680 HCl

Adenosine A2A Receptor Agonist

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Catalog No. A11619

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CGS 21680 hydrochloride 5mg A11619-5
CGS 21680 hydrochloride 10mg A11619-10
CGS 21680 hydrochloride 25mg A11619-25
CGS 21680 hydrochloride 50mg A11619-50
CGS 21680 hydrochloride 10mM * 1mL in DMSO A11619-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CGS 21680 is a specific adenosine A2A subtype receptor agonist.

CGS 21680 HCl

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Publications citing Adooq Products
CGS 21680 HCl Citations (1)
  • Qian Wang, .et al. cAMP-producing chemogenetic and adenosine A2a receptor activation inhibits the inwardly rectifying potassium current in striatal projection neurons, Neuropharmacology, 2019, 148: 229-243 PMID: 30659840

Chemical Information

Catalog Num A11619
Actions Agonist
M. Wt 535.99
Formula C23H29N7O6.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 124182-57-6
Synonyms CGS-21680
SMILES CCNC(=O)[[email protected]@H]1[[email protected]]([[email protected]]([[email protected]@H](O1)N2C=NC3=C2N=C(N=C3N)NCCC4=CC=C(C=C4)CCC(=O)O)O)O.Cl

Biological Activity

CGS 21680 is a specific adenosine A2A subtype receptor agonist.


Solubility (25°C) * In vitro DMSO 107 mg/mL (199.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.66 mL 93.29 mL 186.57mL
0.5 mM 3.73 mL 18.66 mL 37.31 mL
1 mM 1.87 mL 9.33 mL 18.66 mL
5 mM 0.37 mL 1.87 mL 3.73 mL

*The above data is based on the productmolecular weight 535.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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