CNX-1351

Catalog No.: A13879

PI3Kα inhibitor

CNX-1351

CNX-1351 Chemical Structure

CAS NO. 1276105-89-5

CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor with IC50 of 6.8 nM.

Availability: In stock

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5 mg
$90.00
10 mg
$160.00
25 mg
$320.00
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Biological Activity

CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor with IC50 of 6.8 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.44 mL 87.22 mL 174.44 mL
0.5 mM 3.49 mL 17.44 mL 34.89 mL
1 mM 1.74 mL 8.72 mL 17.44 mL
5 mM 0.35 mL 1.74 mL 3.49 mL

*The above data is based on the productmolecular weight 573.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13879
Actions Inhibitor
CAS No. 1276105-89-5
Formula C30H35N7O3S
M. Wt 573.25
Purity >98%
Synonyms CNX1351, CNX 1351
SMILES CC(=CC(=O)CCC(=O)N1CCN(CC1)Cc1cc2c(s1)c(nc(n2)c1cccc2c1cn[nH]2)N1CCOCC1)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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