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Biological Activity
CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor with IC50 of 6.8 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.44 mL | 87.22 mL | 174.44 mL |
| 0.5 mM | 3.49 mL | 17.44 mL | 34.89 mL |
| 1 mM | 1.74 mL | 8.72 mL | 17.44 mL |
| 5 mM | 0.35 mL | 1.74 mL | 3.49 mL |
*The above data is based on the productmolecular weight 573.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13879 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1276105-89-5 |
| Formula | C30H35N7O3S |
| M. Wt | 573.25 |
| Purity | >98% |
| Synonyms | CNX1351, CNX 1351 |
| SMILES | CC(=CC(=O)CCC(=O)N1CCN(CC1)Cc1cc2c(s1)c(nc(n2)c1cccc2c1cn[nH]2)N1CCOCC1)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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