Cobicistat (GS-9350)

Catalog No.: A11277

CYP3A Inhibitor

Cobicistat (GS-9350)

Cobicistat (GS-9350) Chemical Structure

CAS NO. 1004316-88-4

Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $100.00

Special Price $90.00

5 mg

Regular Price: $160.00

Special Price $144.00

10 mg

Regular Price: $210.00

Special Price $189.00

25 mg

Regular Price: $380.00

Special Price $342.00

10mM * 1mL in DMSO

Regular Price: $180.00

Special Price $162.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate.
Targets
CYP3A
30 nM-285 nM
In vitro DMSO 100 mg/mL (128.86 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (128.86 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.05 mL 65.27 mL 130.55 mL
0.5 mM 2.61 mL 13.05 mL 26.11 mL
1 mM 1.31 mL 6.53 mL 13.05 mL
5 mM 0.26 mL 1.31 mL 2.61 mL

*The above data is based on the productmolecular weight 766.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11277
Actions Inhibitor
M. Wt 766.0
Formula C40H53N7O5S2
Solubility DMSO
Purity >99%
Storage at -20°C 3 years Powder
CAS No. 1004316-88-4
Synonyms GS9350
SMILES CC(C)C1=NC(=CS1)CN(C)C(=O)N[[email protected]@H](CCN2CCOCC2)C(=O)N[[email protected]](CC[[email protected]](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Cobicistat (GS-9350) | Cobicistat (GS-9350) Supplier | purchase Cobicistat (GS-9350) | Cobicistat (GS-9350) cost | Cobicistat (GS-9350) manufacturer | order Cobicistat (GS-9350) | Cobicistat (GS-9350) distributor | buy 1004316-88-4| 1004316-88-4 Supplier | purchase 1004316-88-4 | 1004316-88-4 cost | 1004316-88-4 manufacturer | order 1004316-88-4 | 1004316-88-4 distributor
Rewards