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HDAC inhibitor

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Catalog No. A10246

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CUDC-101 10mg A10246-10

Regular Price: $70.00

Special Price: $63.00

CUDC-101 50mg A10246-50

Regular Price: $260.00

Special Price: $234.00

CUDC-101 100mg A10246-100

Regular Price: $480.00

Special Price: $432.00

CUDC-101 200mg A10246-200

Regular Price: $720.00

Special Price: $648.00

CUDC-101 10mM * 1mL in DMSO A10246-10mM-D

Regular Price: $89.00

Special Price: $80.10

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CUDC-101 is a novel compound which inhibits multiple targets, which is designed to inhibit HDAC, EGFR and Her2.


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Chemical Information

Catalog Num A10246
Actions Inhibitor
M. Wt 434.5
Formula C24H26N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1012054-59-9
Synonyms CUDC101

Biological Activity

CUDC-101 is a novel compound which inhibits multiple targets, which is designed to inhibit HDAC, EGFR and Her2.
Target Value
EGFRIC50: 2.4nM
HDACIC50: 4.4nM
HDAC1IC50: 4.5nM
HDAC6IC50: 5.1nM
HDAC3IC50: 9.1nM
HDAC5IC50: 11.4nM
HDAC2IC50: 12.6nM
HDAC4IC50: 13.2nM
HER2IC50: 15.7nM
HDAC10IC50: 26.1nM
HDAC9IC50: 67.2nM
HDAC8IC50: 79.8nM
HDAC7IC50: 373nM


Solubility (25°C) * In vitro DMSO 20 mg/mL (46.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.01 mL 115.07 mL 230.15mL
0.5 mM 4.6 mL 23.01 mL 46.03 mL
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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