Catalog No.: A10249
Hedgehog signaling inhibitor
Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.
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Cyclopamine 5mg
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Cyclopamine 10mg
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Cyclopamine 50mg
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Biological Activity
Discription Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.
Target Value
Product Information
Catalog Num A10249
Formula C27H41NO2
Molecular Weight 411.6
CAS Number 4449-51-8
SMILES C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1
Synonyms 11-deoxojervine

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO Insoluble
Water DMF Warmed: 9 mg/mL (21.86 mM)
Ethanol Warmed: 2 mg/mL (4.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.3 mL 121.48 mL 242.95 mL
0.5 mM 4.86 mL 24.3 mL 48.59 mL
1 mM 2.43 mL 12.15 mL 24.3 mL
5 mM 0.49 mL 2.43 mL 4.86 mL
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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