Biological Activity
Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.
Targets
Smoothened (TM3Hh12 cells) | ||||
46 nM |
In vitro | DMSO | Insoluble | |
Water | DMF Warmed: 9 mg/mL (21.86 mM) | ||
Ethanol | Warmed: 2 mg/mL (4.85 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.3 mL | 121.48 mL | 242.95 mL |
0.5 mM | 4.86 mL | 24.3 mL | 48.59 mL |
1 mM | 2.43 mL | 12.15 mL | 24.3 mL |
5 mM | 0.49 mL | 2.43 mL | 4.86 mL |
*The above data is based on the productmolecular weight 411.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10249 |
---|---|
Actions | Inhibitor |
CAS No. | 4449-51-8 |
Formula | C27H41NO2 |
M. Wt | 411.6 |
Solubility | DMSO |
Purity | >98% |
Synonyms | 11-deoxojervine |
SMILES | C[[email protected]]1C[[email protected]@H]2[[email protected]]([[email protected]]([[email protected]]3(O2)CC[[email protected]]4[[email protected]@H]5CC=C6C[[email protected]](CC[[email protected]@]6([[email protected]]5CC4=C3C)C)O)C)NC1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Cyclopamine | Cyclopamine Supplier | purchase | cost | manufacturer | order | distributor | buy 4449-51-8| 4449-51-8 Supplier | purchase 4449-51-8 | 4449-51-8 cost | 4449-51-8 manufacturer | order 4449-51-8 | 4449-51-8 distributor