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$0.00 Biological Activity
Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.
Targets
| Smoothened (TM3Hh12 cells) | ||||
| 46 nM |
| In vitro | DMSO | Insoluble | |
| Water | DMF Warmed: 9 mg/mL (21.86 mM) | ||
| Ethanol | Warmed: 2 mg/mL (4.85 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.3 mL | 121.48 mL | 242.95 mL |
| 0.5 mM | 4.86 mL | 24.3 mL | 48.59 mL |
| 1 mM | 2.43 mL | 12.15 mL | 24.3 mL |
| 5 mM | 0.49 mL | 2.43 mL | 4.86 mL |
*The above data is based on the productmolecular weight 411.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10249 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 4449-51-8 |
| Formula | C27H41NO2 |
| M. Wt | 411.6 |
| Purity | >98% |
| Synonyms | 11-deoxojervine |
| SMILES | C[[email protected]]1C[[email protected]@H]2[[email protected]]([[email protected]]([[email protected]]3(O2)CC[[email protected]]4[[email protected]@H]5CC=C6C[[email protected]](CC[[email protected]@]6([[email protected]]5CC4=C3C)C)O)C)NC1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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