Total item
Cart Subtotal
$0.00 Black Friday & Year End Sale starting Nov 21st 2022 through Jan 2nd 2023, enjoy 20% off sitewide
Biological Activity
CYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ± 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing.
Targets
| Microtubules (cancer cell lines) | ||||
| 10 nM-100 nM |
| In vitro | DMSO | 77 mg/mL (177.2 mM) | |
| Water | Insoluble | ||
| Ethanol | 18 mg/mL (41.42 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.01 mL | 115.07 mL | 230.15 mL |
| 0.5 mM | 4.6 mL | 23.01 mL | 46.03 mL |
| 1 mM | 2.3 mL | 11.51 mL | 23.01 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10264 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 917111-44-5 |
| Formula | C24H30N6O2 |
| M. Wt | 434.5 |
| Purity | >98% |
| Synonyms | CYT-997, Lexibulin |
| SMILES | CCC[[email protected]@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy CYT997 (Lexibulin) | CYT997 (Lexibulin) Supplier | purchase | cost | manufacturer | order | distributor | buy 917111-44-5| 917111-44-5 Supplier | purchase 917111-44-5 | 917111-44-5 cost | 917111-44-5 manufacturer | order 917111-44-5 | 917111-44-5 distributor
Adooq Quality Guarantee
We promise all products perform as described.