D-69491

Catalog No.: A15457

HER2 inhibitor

D-69491

D-69491 Chemical Structure

CAS NO. 346599-65-3

D-69491 (SU11464) is a small-molecule HER2 inhibitor, which was under development for the treatment of tumours with high expression of HER2, such as breast, ovarian, lung and pancreatic carcinomas.

Availability: In stock

Package Price Qty
2 mg
$200.00
5 mg
$400.00
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Biological Activity

D-69491 (SU11464) is a small-molecule HER2 inhibitor, which was under development for the treatment of tumours with high expression of HER2, such as breast, ovarian, lung and pancreatic carcinomas.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.78 mL 88.9 mL 177.8 mL
0.5 mM 3.56 mL 17.78 mL 35.56 mL
1 mM 1.78 mL 8.89 mL 17.78 mL
5 mM 0.36 mL 1.78 mL 3.56 mL

*The above data is based on the productmolecular weight 562.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15457
Actions Inhibitor
CAS No. 346599-65-3
Formula C25H26Cl2FN7O3
M. Wt 562.42
Purity >98%
Synonyms D69491, SU 11464, SU11464, D 69491
SMILES CC1=C(NC(=C1)C(=O)NCCN2CCOCC2)C=C3C4=C(NC3=O)N=CN=C4NC5=CC(=C(C=C5)F)Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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