AMG-073 HCl (Cinacalcet HCl)Catalog No. A10219
Quick Overview
AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium.
Products are for laboratory research use only. Not for human use. We do not sell to patients.
Product Information
| Catalog Num | A10219 |
|---|---|
| M. Wt | 393.9 |
| Formula | C22H23ClF3N |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 364782-34-3 |
| Synonyms | Mimpara, Sensipar |
| Chemical Name | |
| SMILES Code | C[[email protected]](C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl |
Biological activity
Introduction |
AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. | ||||||||||
Targets |
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Solubility
| Solubility (25C) * | In vitro | DMSO | 79 mg/mL (200.57 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 33 mg/mL (83.78 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Return Policy | Contact information |
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