Cisplatin

Catalog No. A10221

Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
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Catalog Num A10221
M. Wt 300.1
Formula Cl2H4N2Pt
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 15663-27-1
Synonyms cisplatinum, CDDP, cis-diamminedichloroplatinum(II)
SMILES N.N.Cl[Pt+2]Cl
Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
Targets
DNA synthesis (Tumor cells)
In vitro DMSO 60 mg/mL (199.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.32 mL 166.61 mL 333.22 mL
0.5 mM 6.66 mL 33.32 mL 66.64 mL
1 mM 3.33 mL 16.66 mL 33.32 mL
5 mM 0.67 mL 3.33 mL 6.66 mL

*The above data is based on the productmolecular weight 300.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.