Phloretin (Dihydronaringenin)

Catalog No. A10723

Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin.
Catalog Num A10723
M. Wt 274.3
Formula C15H14O5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 60-82-2
Synonyms Dihydronaringenin, Phloretol
SMILES C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin.
Targets
SGLT1 SGLT2
In vitro DMSO 55 mg/mL (200.53 mM)
Water <1 mg/mL (<1 mM)
Ethanol 55 mg/mL (200.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.46 mL 182.28 mL 364.56 mL
0.5 mM 7.29 mL 36.46 mL 72.91 mL
1 mM 3.65 mL 18.23 mL 36.46 mL
5 mM 0.73 mL 3.65 mL 7.29 mL

*The above data is based on the productmolecular weight 274.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.