PIK-294Catalog No. A10728

Quick Overview

PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported.
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PIK-294

Product Information
Catalog Num A10728
M. Wt 489.5
Formula C28H23N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 900185-02-6
Synonyms PIK294
SMILES Code CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=C(C(=N4)C6=CC(=CC=C6)O)C(=NC=N5)N

Biological activity
Introduction
PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported.
Targets
p110δ p110γ p110β
10 nM160 nM490 nM
Solubility
Solubility (25C)* In vitro DMSO 98 mg/mL (200.19 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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