Telaprevir (VX-950)Catalog No. A10902

Quick Overview

Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.
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Telaprevir (VX-950)

Telaprevir (VX-950)  Citations(3)
  • Jacobs CL, .et al. StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins, Nat Methods, 2018, Jul;15(7):523-526 PMID: 29967496
  • Apriyanto DR, .et al. Anti-Hepatitis C Virus Activity of a Crude Extract from Longan (Dimocarpus longan Lour.) Leaves, Jpn J Infect Dis, 2016, May 20;69(3):213-20 PMID: 26255732
  • Mizuki Yamamoto, .et al. Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay, Antimicrob Agents Chemother, 2016, Nov; 60(11): 6532-6539 PMID: 27550352
  • Product Information
    Catalog Num A10902
    M. Wt 679.9
    Formula C36H53N7O6
    Solubility DMSO
    Purity >98%
    Storage at -20°C 3 years Powder
    CAS No. 402957-28-2
    Synonyms VX950, Incivek, Incivo
    SMILES Code CCC[[email protected]@H](C(=O)C(=O)NC1CC1)NC(=O)[[email protected]@H]2[[email protected]]3CCC[[email protected]]3CN2C(=O)[[email protected]](C(C)(C)C)NC(=O)[[email protected]](C4CCCCC4)NC(=O)C5=NC=CN=C5

    Biological activity
    Introduction
    Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.
    Targets
    HCV NS3-4A serine protease
    0.35 μM
    Solubility
    Solubility (25C) * In vitro DMSO 136 mg/mL (200.04 mM)
    Water <1 mg/mL (<1 mM)
    Ethanol <1 mg/mL (<1 mM)
    In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Return Policy Contact information
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    High Purity Kinase Inhibitors on Signaling Pathways

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