Topotecan HCl (Hycamtin)

Catalog No. A10939

Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.
Catalog Num A10939
M. Wt 457.9
Formula C23H23N3O5 .HCl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 119413-54-6
Synonyms Hycamtin
SMILES CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl
Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.
In vitro (25°C) DMSO 92 mg/mL (200.91 mM)
Water 92 mg/mL (200.91 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.84 mL 109.19 mL 218.39 mL
0.5 mM 4.37 mL 21.84 mL 43.68 mL
1 mM 2.18 mL 10.92 mL 21.84 mL
5 mM 0.44 mL 2.18 mL 4.37 mL

*The above data is based on the productmolecular weight 457.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.