Vatalanib (PTK787) 2HClCatalog No. A10967
Quick Overview
Vatalanib (PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis that inhibits all known VEGF receptors, as well as platelet-derived growth factor receptor-beta and c-kit, but is most selective for VEGFR-2.
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Product Information
| Catalog Num | A10967 |
|---|---|
| M. Wt | 419.7 |
| Formula | C20H17Cl3N4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 212141-54-3 |
| Synonyms | Vatalanib,PTK787,PTK/ZK |
| Chemical Name | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride |
| SMILES Code | C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl |
Biological activity
Introduction |
Vatalanib (PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis that inhibits all known VEGF receptors, as well as platelet-derived growth factor receptor-beta and c-kit, but is most selective for VEGFR-2. | ||||||||||||||||
Targets |
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Solubility
| Solubility (25C)* | In vitro | DMSO | 85 mg/mL (202.51 mM) |
|---|---|---|---|
| Water | 10 mg/mL (23.82 mM) | ||
| Ethanol | 6 mg/mL (14.29 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Return Policy | Contact information |
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