MK-4827 (Niraparib)Catalog No. A11026

Quick Overview

MK-4827 is a novel potent, orally bioavailable PARP-1 and PARP-2 inhibitor.
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MK-4827 (Niraparib)

MK-4827 (Niraparib)  Citations(3)
  • Bian C, .et al. NADP+ is an endogenous PARP inhibitor in DNA damage response and tumor suppression, Nat Commun, 2019, Feb 11;10(1):693 PMID: 30741937
  • Tahira Baloch, .et al. Sequential therapeutic targeting of ovarian Cancer harboring dysfunctional BRCA1, BMC Cancer, 2019, Jan 10;19(1):44 PMID: 30630446
  • Khalid Hilmi, .et al. CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair, Sci Adv, 2017, May; 3(5): e1601898 PMID: 28560323
  • Product Information
    Catalog Num A11026
    M. Wt 320.4
    Formula C19H20N4O
    Solubility DMSO
    Purity >98%
    Storage at -20°C 3 years Powder
    CAS No. 1038915-60-4
    Synonyms MK4827
    SMILES Code C1C[[email protected]](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N

    Biological activity
    Introduction
    MK-4827 is a novel potent, orally bioavailable PARP-1 and PARP-2 inhibitor.
    Return Policy Contact information
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