LY2109761Catalog No. A11133

Quick Overview

LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis
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LY2109761

LY2109761  Citations(2)
  • Uto T, .et al. Critical role of plasmacytoid dendritic cells in induction of oral tolerance, J Allergy Clin Immunol, 2018, Jun;141(6):2156-2167.e9 PMID: 29477579
  • Jared M. Fischer, .et al. Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation, Proc Natl Acad Sci U S A, 2016, Oct 25; 113(43): 12192-12197 PMID: 27791005
  • Product Information
    Catalog Num A11133
    M. Wt 441.5
    Formula C26H27N5O2
    Solubility DMSO
    Purity >98%
    Storage at -20°C 3 years Powder
    CAS No. 700874-71-1
    Synonyms LY-2109761
    SMILES Code C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6

    Biological activity
    Introduction
    LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis
    Solubility
    Solubility (25C) * In vitro DMSO 2 mg/mL (4.52 mM)
    Water <1 mg/mL (<1 mM)
    Ethanol <1 mg/mL (<1 mM)
    In vivo 0.5% CMC/0.25% Tween 80 16 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Return Policy Contact information
    Adooq Bioscience has Satisfaction Guarantee return policy. You may return/exchange any items within 365 days from the original purchase date if you are not satisfied with your purchase, either for protocol related or product related problems.

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    >>Prior to returning any items, please contact the Customer Service ([email protected]) to obtain an Return/Exchange Authorization. Items returned without prior authorization may not be accepted. Any items returned to Adooq should be in the original packaging and in the same condition as originally purchased.


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    High Purity Kinase Inhibitors on Signaling Pathways

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