Odanacatib (MK-0822)

Catalog No. A11265

Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.
Catalog Num A11265
M. Wt 525.6
Formula C25H27F4N3O3S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 603139-19-1
Synonyms MK0822
SMILES CC(C)(C[[email protected]@H](C(=O)NC1(CC1)C#N)N[[email protected]@H](C2=CC=C(C=C2)C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F
Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.
Targets
Cathepsin K (human) Cathepsin K (rabbit)
0.2 nM1 nM
In vitro (25°C) DMSO 100 mg/mL (190.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.03 mL 95.13 mL 190.26 mL
0.5 mM 3.81 mL 19.03 mL 38.05 mL
1 mM 1.9 mL 9.51 mL 19.03 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.