Asunaprevir (BMS-650032)Catalog No. A11295

Quick Overview

Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.
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Asunaprevir (BMS-650032)

Asunaprevir (BMS-650032)  Citations(5)
  • Fay EJ, .et al. Engineered Small-Molecule Control of Influenza A Virus Replication, J Virol, 2018, Fay EJ PMID: 30282710
  • Bennie Lemmens, .et al. DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation, Mol Cell, 2018, Jul 5; 71(1): 117–128.e3 PMID: 30008317
  • Ueda Y, .et al. Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems, Virus Res, 2017, May 2;235:37-48 PMID: 28322919
  • Furihata T, .et al. Differential inhibition features of direct-acting anti-hepatitis C virus agents against human organic anion transporting polypeptide 2B1, Int J Antimicrob Agents, 2015, Oct;46(4):381-8 PMID: 26163159
  • Tomomi Furihata, .et al. Different Interaction Profiles of Direct-Acting Anti-Hepatitis C Virus Agents with Human Organic Anion Transporting Polypeptides, Antimicrob Agents Chemother, 2014, 58(8): 4555–4564. PMID: 24867984
  • Product Information
    Catalog Num A11295
    M. Wt 748.3
    Formula C35H46ClN5O9S
    Solubility DMSO
    Purity >98%
    Storage at -20°C 3 years Powder
    CAS No. 630420-16-5
    Synonyms BMS650032, ASV
    Chemical Name 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropyl}-L-prolinamide
    SMILES Code CC(C)(C)C(C(=O)N1CC(CC1C(=O)NC2(CC2C=C)C(=O)NS(=O)(=O)C3CC3)OC4=NC=C(C5=C4C= C(C=C5)Cl)OC)NC(=O)OC(C)(C)C

    Biological activity
    Introduction
    Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.
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    High Purity Kinase Inhibitors on Signaling Pathways

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