CPI-613

Catalog No. A11786

CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities.
  • Egawa Y, .et al. Therapeutic potential of CPI-613 for targeting tumorous mitochondrial energy metabolism and inhibiting autophagy in clear cell sarcoma, PLoS One, 2018, Jun 7;13(6):e0198940 PMID: 29879220
Catalog Num A11786
M. Wt 388.6
Formula C22H28O2S2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 95809-78-2
Synonyms CPI613
SMILES C1=CC=C(C=C1)CSCCC(CCCCC(=O)O)SCC2=CC=CC=C2
CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities.
Targets
PDH (NCI-H460 cells) α-ketoglutarate dehydrogenase (NCI-H460 cells)
In vitro (25°C) DMSO 78 mg/mL (200.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol 78 mg/mL (200.72 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.73 mL 128.67 mL 257.33 mL
0.5 mM 5.15 mL 25.73 mL 51.47 mL
1 mM 2.57 mL 12.87 mL 25.73 mL
5 mM 0.51 mL 2.57 mL 5.15 mL

*The above data is based on the productmolecular weight 388.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.