Ki16198

Catalog No. A11966

Ki16198 is a potent LPA receptor antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively.
Catalog Num A11966
M. Wt 488.98
Formula C24H25ClN2O5S
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 355025-13-7
Synonyms Ki-16198
SMILES CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)OC
Ki16198 is a potent LPA receptor antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively.
Targets
LPA1 LPA3
0.34 μM(Ki)0.93 μM(Ki)
In vitro (25°C) DMSO 86 mg/mL (175.87 mM)
Water Insoluble
Ethanol 32 mg/mL (65.44 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.45 mL 102.25 mL 204.51 mL
0.5 mM 4.09 mL 20.45 mL 40.9 mL
1 mM 2.05 mL 10.23 mL 20.45 mL
5 mM 0.41 mL 2.05 mL 4.09 mL

*The above data is based on the productmolecular weight 488.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.