TMS

Catalog No. A11977

TMS is a potent, selective and competitive inhibitor of cytochrome P450 1B1, an enzyme overexpressed in certain tumors (IC50= 6 nM). 5N/A- and 520-fold selective over P450 1A1 and 1A2 respectively.
Catalog Num A11977
M. Wt 300.35
Formula C18H20O4
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 24144-92-1
Synonyms E)-2,3',4,5'-tetramethoxystilbene
SMILES COC1=CC(=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)OC
TMS is a potent, selective and competitive inhibitor of cytochrome P450 1B1, an enzyme overexpressed in certain tumors (IC50= 6 nM). 5N/A- and 520-fold selective over P450 1A1 and 1A2 respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.29 mL 166.47 mL 332.94 mL
0.5 mM 6.66 mL 33.29 mL 66.59 mL
1 mM 3.33 mL 16.65 mL 33.29 mL
5 mM 0.67 mL 3.33 mL 6.66 mL

*The above data is based on the productmolecular weight 300.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.