INNO-206 (Aldoxorubicin)

Catalog No. A12326

Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity.
  • Dos Santos Câmara AL, .et al. Acid-sensitive lipidated doxorubicin prodrug entrapped in nanoemulsion impairs lung tumor metastasis in a breast cancer model, Nanomedicine (Lond), 2017, Aug;12(15):1751-1765 PMID: 28703043
Catalog Num A12326
M. Wt 750.75
Formula C37H42N4O13
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 151038-96-9
Synonyms DOXO-EMCH, INNO-2N/A6, INNO2N/A6; INNO 2N/A6; Aldoxorubicin
SMILES C[[email protected]]1[[email protected]]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(/C(=N\NC(=O)CCCCCN6C(=O)C=CC6=O)/CO)O)N)O
Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.32 mL 66.6 mL 133.2 mL
0.5 mM 2.66 mL 13.32 mL 26.64 mL
1 mM 1.33 mL 6.66 mL 13.32 mL
5 mM 0.27 mL 1.33 mL 2.66 mL

*The above data is based on the productmolecular weight 750.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.