Halofuginone

Catalog No. A12441

Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities.
Catalog Num A12441
M. Wt 414.68
Formula C16H17BrClN3O3
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 55837-20-2
Synonyms Tempostatin; RU 19110
SMILES C1C[[email protected]]([[email protected]@H](NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O
Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities.
Targets
prolyl-tRNA synthetase
18.3nM(Ki)
In vitro DMSO 17 mg/mL (40.99 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.11 mL 120.57 mL 241.15 mL
0.5 mM 4.82 mL 24.11 mL 48.23 mL
1 mM 2.41 mL 12.06 mL 24.11 mL
5 mM 0.48 mL 2.41 mL 4.82 mL

*The above data is based on the productmolecular weight 414.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.