SCH 442416Catalog No. A12695
Quick Overview
SCH 442416 is a selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM).
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Product Information
| Catalog Num | A12695 |
|---|---|
| M. Wt | 389.42 |
| Formula | C20H19N7O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 316173-57-6 |
| Synonyms | SCH442416, SCH-442416 |
| Chemical Name | 2-(2-Furanyl)-7-[3-(4-methoxyphenyl?)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]p?yrimidin-5-amine |
| SMILES Code | COC1=CC=C(C=C1)CCCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5 |
Biological activity
Introduction |
SCH 442416 is a selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM). |
| Return Policy | Contact information |
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