(+)-JQ1Catalog No. A12729

Quick Overview

(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.
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(+)-JQ1  Citations(2)
  • A Carrer, .et al. Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis, Cancer Discov, 2019, Jan 9. pii: CD-18-0567 PMID: 30626590
  • Clocchiatti A, .et al. Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation, J Clin Invest, 2018, Dec 3;128(12):5531-5548 PMID: 30395538
  • Product Information
    Catalog Num A12729
    M. Wt 456.99
    Formula C23H25ClN4O2S
    Solubility DMSO
    Purity >98%
    Storage at -20°C 3 years Powder
    CAS No. 1268524-70-4
    Synonyms N/A
    SMILES Code CC1=C(SC2=C1C(=N[[email protected]](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C

    Biological activity
    (+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.
    Solubility (25C)* In vitro DMSO 91 mg/mL (199.12 mM)
    Water <1 mg/mL (<1 mM)
    Ethanol 91 mg/mL (199.12 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Return Policy Contact information
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    High Purity Kinase Inhibitors on Signaling Pathways

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