StemRegenin 1 (SR1)

Catalog No. A12945

StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).
Catalog Num A12945
M. Wt 466
Formula C24H23N5OS?HCl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1227633-49-9
Synonyms SR-1
SMILES CC(C)N1C=NC2=C1N=C(N=C2NCCC3=CC=C(C=C3)O)C4=CSC5=CC=CC=C54
StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).
Targets
Aryl hydrocarbon receptor (AhR) ()
127 nM
In vitro DMSO 86 mg/mL (200.21 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.46 mL 107.3 mL 214.59 mL
0.5 mM 4.29 mL 21.46 mL 42.92 mL
1 mM 2.15 mL 10.73 mL 21.46 mL
5 mM 0.43 mL 2.15 mL 4.29 mL

*The above data is based on the productmolecular weight 466. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.