PD 123319 ditrifluoroacetate

Catalog No. A13201

PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.
  • Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
Catalog Num A13201
M. Wt 736.67
Formula C31H32N4O3.2CF3CO2H
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 130663-39-7
Synonyms PD123319, PD-123319
SMILES CC1=C(C=CC(=C1)CN2C=NC3=C2C[[email protected]](N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C
PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.
Targets
AT2 receptor
34 nM
In vitro (25°C) DMSO 87 mg/mL (171.05 mM)
Water 87 mg/mL (171.05 mM)
Ethanol 87 mg/mL (171.05 mM)
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.57 mL 67.87 mL 135.75 mL
0.5 mM 2.71 mL 13.57 mL 27.15 mL
1 mM 1.36 mL 6.79 mL 13.57 mL
5 mM 0.27 mL 1.36 mL 2.71 mL

*The above data is based on the productmolecular weight 736.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.