Actinomycin DCatalog No. A13239

Quick Overview

Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria.
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Actinomycin D

Actinomycin D  Citations(1)
  • Chauhan D,et al. BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1汕 Maturation in Macrophages, Cell Rep, 2018, Nov 27;25(9):2354-2368.e5 30485805
  • Product Information
    Catalog Num A13239
    M. Wt 1255.4
    Formula C62H86N12O16
    Solubility DMSO
    Purity >98%
    Storage at -20°C 3 years Powder
    CAS No. 50-76-0
    Synonyms Actinomycin-D
    Chemical Name 2-Amino-(N,N)-1-bis(hexadecahydro-6?,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentao?xo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-ox?o-3H-phenoxazine-1,9-dicarboxamide
    SMILES Code CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C

    Biological activity
    Introduction
    Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria.
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