E 64d (Aloxistatin)

Catalog No. A13259

E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.
  • Paudel DB, .et al. Expression and antiviral function of ARGONAUTE 2 in Nicotiana benthamiana plants infected with two isolates of tomato ringspot virus with varying degrees of virulence, Virology, 2018, Nov;524:127-139 PMID: 30195250
Catalog Num A13259
M. Wt 342.43
Formula C17H30N2O5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 88321-09-9
Synonyms E-64d, E64d
SMILES CCOC(=O)[[email protected]@H]1[[email protected]](O1)C(=O)N[[email protected]@H](CC(C)C)C(=O)NCCC(C)C
E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.
Targets
Cysteine protease
In vitro DMSO 68 mg/mL (198.58 mM)
Water <1 mg/mL (<1 mM)
Ethanol 68 mg/mL (198.58 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.2 mL 146.02 mL 292.03 mL
0.5 mM 5.84 mL 29.2 mL 58.41 mL
1 mM 2.92 mL 14.6 mL 29.2 mL
5 mM 0.58 mL 2.92 mL 5.84 mL

*The above data is based on the productmolecular weight 342.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.