NU 9056

Catalog No. A13378

NU9056 is an selective KAT5 (Tip60) HAT inhibitor. IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively. Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.
Catalog Num A13378
M. Wt 232.37
Formula C6H4N2S4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. Not Available
Synonyms NU9056, NU-9056
SMILES C1(SSC2=CC=NS2)=CC=NS1
NU9056 is an selective KAT5 (Tip60) HAT inhibitor. IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively. Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.03 mL 215.17 mL 430.35 mL
0.5 mM 8.61 mL 43.03 mL 86.07 mL
1 mM 4.3 mL 21.52 mL 43.03 mL
5 mM 0.86 mL 4.3 mL 8.61 mL

*The above data is based on the productmolecular weight 232.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.