PF-4618433
Catalog No. A13461
PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.
| Catalog Num | A13461 |
|---|---|
| M. Wt | 445.52 |
| Formula | C24H27N7O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1166393-85-6 |
| Synonyms | PF 4618433, PF4618433 |
| SMILES | Cc1ccc(cc1)n2c(cc(n2)C(C)(C)C)NC(=O)Nc3cc(n[nH]3)COc4cccnc4 |
PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.45 mL | 112.23 mL | 224.46 mL |
| 0.5 mM | 4.49 mL | 22.45 mL | 44.89 mL |
| 1 mM | 2.24 mL | 11.22 mL | 22.45 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.49 mL |
*The above data is based on the productmolecular weight 445.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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